How to choose a right dressing

Moisture wound healing theory

Moist wound healing is the practice of keeping a wound in an optimally moist environment in order to promote faster healing.

  • Favorable for the dissolution of necrotic tissue
    A. Hydrate with exudate to release plasmin
    B. Dissolve the fibrous sheath around small blood vessels and restore normal nutrient exchange
    C. Immune cell chemokines, accelerate debridement
  • Hypoxic condition of maintaining local microenvironment of wound
  • Help cell proliferation, differentiation and migration
    A. Maintain cell and enzyme activity
    B. Rapid cell migration
  • Retention of growth factors in exudates and promotion of their release.
    A. Stimulate the proliferation of fibroblasts
    B. Chemotactic agent for macrophages and neutrophils
  • Keep wound temperature close or same as human body temperature:37
    A. The mitotic rate of cells increased by 108%.
  • Keep wound moist
    B. No form scab and avoid twice machanical damage.
    C. Avoid exposure of nerve endings to air and reduce pain
  • Lower infection rate
    A. Occlusive dressing, block outside microbe.
    B. Moist wound infection rate 2.6%
    C. Dry wound infection rate 7.1%
  • The problem of saturated absorption or excessive stickiness of the dressing and staying on the wound:
    • Wound Maceration
    • Dressing leakage
    • Damage surrounding skin

Wound bed preparation

Complex” wounds

Wound bed” preparation

  • Tissue management
  • Infection management
  • Exudate management
  • Edge of wound

Wound bed” preparation complete

Normal” wounds

How to choose a right dressing

Dressings should be selected based on the characteristics of the wound.

Wound type by Color of wound

Black wound: Necrotic tissue lacking blood supply, soft or hard, scabby, with little or no exudate.

Yellow wound: Carrion/Slough, exudate, or infection
Yellow wound

Red wound: Granulomatous tissue with healthy blood flow, clean, healing

Red wound

Pink wound:

  • pink epithelial tissues
  • The neoepithelial tissue is delicate and in the stage of skin climbing.
Pink wound
Exudate level during time scheme

Alginate dressing and CMC dressings, which are useful for moderate to heavily exuding wounds, are primary dressings designed for use on wounds with moderate to heavy drainage.
A superabsorbent dressing can be a primary or secondary dressing which manages moderate to heavy wound exudate.
CMC dressing, foam dressing, transparent PU dressing are secondary dressings.
The longer wear time of these dressings minimizes the number of times the wound bed is disturbed which may improve healing outcomes.
Cost effectiveness should always be considered when selecting a dressing, however the least expensive dressing may not be the most cost effective. Longer wear time reduces clinician labor costs, a significant factor in overall wound care costs.
Dressing selection should be based on the needs of the wound to obtain the best outcomes for healing.

Clinical use cases of hemodialysis + hemoperfusion.

Case Description:

Male, 65 year-old, from the Blood Purification Center of Central Hospital, with a history of hemodialysis for 3 years. She received hemoperfusion treatment, but had to give up because of adverse reactions. The patient relies on drug control and blood filtration to relieve the skin itching, but the effect is not very satisfactory. She hopes that hemoperfusion can be used to improve the condition.

Treatment Method

Hemodialysis combined with hemoperfusion therapy, once per week, during which the individual dialysis is maintained 3 times per week for three consecutive weeks. Result: After the first treatment, the patient did not have the adverse reactions when using perfusion devices from other brands. One hour after the hemoperfusion, the patient relaxed physically and mentally and entered a state of sleep. The skin pruritus symptom improved significantly. After the second hemoperfusion, most of the pruritus symptoms have been eliminated, appetite has also been improved, food intake has increased, and no adverse reactions have occurred. After three treatments, the pruritus basically disappeared and there were no adverse reactions. The patient told us that the quality of sleep had improved, with more energy in daily life, the quality of life had improved a lot.

Results:

After the first treatment, the patient did not have the adverse reactions when using perfusion devices from other brands. One hour after the hemoperfusion, the patient relaxed physically and mentally and entered a state of sleep. The skin pruritus symptom improved significantly. After the second hemoperfusion, most of the pruritus symptoms have been eliminated, appetite has also been improved, food intake has increased, and no adverse reactions have occurred. After three treatments, the pruritus basically disappeared and there were no adverse reactions. The patient told us that the quality of sleep had improved, with more energy in daily life, the quality of life had improved a lot.